Abstract
Introduction: Worldwide, cervical cancer is the fourth most frequent cancer in women with an estimated 604 000 new cases and 342,000 deaths in 2020. About 90% of these occur in low- and middle-income countries. In Malaysia, cervical cancer is the 3rd commonest cancer among women and ranks the 7th amongst Malaysians where incidence of cervical cancer has increased from 6.5 per 100,000 population in 2011 year to 10.5 per 100,000 population in 2018. Screening is the key prevention and early detection and treatment for precancerous lesions are important secondary prevention of the disease. The purpose of the study is to explore the acceptability and feasibility of HPV-DNA self-sampling (age group 30-49 years) comparing with the conventional Pap Smear (age group 30-65 years) as an early screening tool for cervical cancer detection among eligable women within the stipulated age group.
Methods: This is a secondary data analysis extracted from Laporan Bulanan/Tahunan Pengambilan Dan Keputusan Pap Smear Mengikut Laporan Makmal 2016-2019 (PKW 202A, PKW202B, Rumusan) and HPV-DNA listings 2019-2020 in Putrajaya Federal Territory. The response rate (uptake rate) of HPV-DNA self-sampling (specimens successfully returned for laboratory testing) is presented in descriptive statistic.
Results: Number of yearly screening PAP smear samples ranged from 931 samples in 2016, 1084 samples in 2017 and 943 samples in 2018. Cumulative number of abnormal results were 22 cases out of 2,958 samples for the 3 years ' worth of screening, making the detection rate at 0.74%. Since the introduction of HPV-DNA self sampling in July 2019 , the response was overwhelming and the screening uptake increased significantly. Within eight months of implementation, a total number of 3,981 women were screened prior to the Covid-19 pandemic (Mac 2020) with a detection rate of 4.5% (179 positive sample of HPV infection). Discussion: HPV-DNA self-sampling as a new screening tool for cervical cancer screening is more feasible and acceptable among women in Putrajaya. Hence, women are likely to come forward to be screened if HPV-DNA self-sampling is used as a method of screening other than the conventional pap smear. Based of the feedback gathered, their overall experience were positive, very convenient, time-saving, and less discomfort. With continuation of HPV-DNA self-sampling as the primary screening tool, it will overcome the barriers including fear or shame, cultural or religious considerations to screening. This will effectively increase screening coverage among those under-screened populations and further aid in reducing the morbidity and mortality of cervical cancer in women, thus as one of the most successfully treatable forms of cancer.
Links
- https://apcph.cphm.my/wp-content/uploads/2022/07/APCPH2022-P-68.pdf
- https://apcph.cphm.my/wp-content/uploads/wpforms/1176-1e04940bb5d885bf8711ed1909[...]
BibTeX (Download)
@proceedings{APCPH2022-P-68,
title = {Ladies, The First Step Starts with You; Stop the Cancer. Empowering Women in Using Human Papillomavirus (HPV) DNA Self-Sampling as Cervical Cancer Screening Through Putrajaya's Lense},
author = {Wan Nur Shazwani Wan Mohamad Nor and Haslinda Rahaman and Nor Filzatun Borhan and Zarirah Adzni Mokhtar},
url = {https://apcph.cphm.my/wp-content/uploads/2022/07/APCPH2022-P-68.pdf
https://apcph.cphm.my/wp-content/uploads/wpforms/1176-1e04940bb5d885bf8711ed19095a89ed/POSTER-APCPH-STOP-THE-CANCER-25.7.2022-3b8dfc7fbd5ed5eeca1168720fa9ac72.pdf},
year = {2022},
date = {2022-08-02},
urldate = {2022-08-02},
issue = {7},
abstract = {Introduction: Worldwide, cervical cancer is the fourth most frequent cancer in women with an estimated 604 000 new cases and 342,000 deaths in 2020. About 90% of these occur in low- and middle-income countries. In Malaysia, cervical cancer is the 3rd commonest cancer among women and ranks the 7th amongst Malaysians where incidence of cervical cancer has increased from 6.5 per 100,000 population in 2011 year to 10.5 per 100,000 population in 2018. Screening is the key prevention and early detection and treatment for precancerous lesions are important secondary prevention of the disease. The purpose of the study is to explore the acceptability and feasibility of HPV-DNA self-sampling (age group 30-49 years) comparing with the conventional Pap Smear (age group 30-65 years) as an early screening tool for cervical cancer detection among eligable women within the stipulated age group.
Methods: This is a secondary data analysis extracted from Laporan Bulanan/Tahunan Pengambilan Dan Keputusan Pap Smear Mengikut Laporan Makmal 2016-2019 (PKW 202A, PKW202B, Rumusan) and HPV-DNA listings 2019-2020 in Putrajaya Federal Territory. The response rate (uptake rate) of HPV-DNA self-sampling (specimens successfully returned for laboratory testing) is presented in descriptive statistic.
Results: Number of yearly screening PAP smear samples ranged from 931 samples in 2016, 1084 samples in 2017 and 943 samples in 2018. Cumulative number of abnormal results were 22 cases out of 2,958 samples for the 3 years ' worth of screening, making the detection rate at 0.74%. Since the introduction of HPV-DNA self sampling in July 2019 , the response was overwhelming and the screening uptake increased significantly. Within eight months of implementation, a total number of 3,981 women were screened prior to the Covid-19 pandemic (Mac 2020) with a detection rate of 4.5% (179 positive sample of HPV infection). Discussion: HPV-DNA self-sampling as a new screening tool for cervical cancer screening is more feasible and acceptable among women in Putrajaya. Hence, women are likely to come forward to be screened if HPV-DNA self-sampling is used as a method of screening other than the conventional pap smear. Based of the feedback gathered, their overall experience were positive, very convenient, time-saving, and less discomfort. With continuation of HPV-DNA self-sampling as the primary screening tool, it will overcome the barriers including fear or shame, cultural or religious considerations to screening. This will effectively increase screening coverage among those under-screened populations and further aid in reducing the morbidity and mortality of cervical cancer in women, thus as one of the most successfully treatable forms of cancer.},
howpublished = {published online at https://apcph.cphm.my},
note = {Type: POSTER PRESENTATION; Organisation: Pejabat Kesihatan Putrajaya, WP Putrajaya, Fakulti Perubatan dan Sains Kesihatan, Universiti Putra Malaysia},
keywords = {cervical cancer, HPV, HPV self sampling, Pap Smear},
pubstate = {published},
tppubtype = {proceedings}
}