Abstract
Introduction: COVID-19 has a varied clinical presentation and may progress to severe form which could be fatal. Previous systematic reviews reported that 19.2% to 21.33% of COVID-19 patients progressed to severe form. Determination of risk factors for severe form of infection would be beneficial in averting COVID-19 mortality in Terengganu setting.
Methods: A case-control study between mild and severe COVID-19 groups was conducted in Terengganu state from 1st March 2020 until 31st January 2021 based on retrospective record review. Cases were severe COVID-19 patients (COVID-19 patients grouped in category IV or V upon diagnosis) while controls were mild COVID-19 patients (COVID-19 patients grouped in category I, II or III upon diagnosis). Individuals with laboratory RT-PCR confirmed positive test for COVID-19 were included as study samples. Descriptive statistics, simple and multiple logistic regression analyses were employed for statistical analysis. Results: There were 2142 COVID-19 cases in Terengganu during the studied period. The proportion of severe COVID-19 infection was 2.1% (95%CI: 0.01, 0.03). Among the severe COVID-19 cases, their mean ( ±SD) age was 52 ( ±16) and majority of them were male (59.1%) and had comorbidity (56.8%). The common symptoms among severe COVID-19 cases included fever (68.2%), cough (63.6%), coryza (22.7%), sore throat (13.6%) and anosmia (11.4%). Multiple logistic regression revealed older age, presence of comorbidity, having symptoms of fever, cough and anosmia as the significant associated factors for severe COVID-19 with adjusted odds ratio (AOR) of 1.07 (95%CI: 1.03, 1.11), p<0.001; AOR 5.97 (95%CI: 2.09, 17.01)
Links
- https://apcph.cphm.my/wp-content/uploads/2022/07/APCPH2022-P-83.pdf
- https://apcph.cphm.my/wp-content/uploads/wpforms/1176-1e04940bb5d885bf8711ed1909[...]
BibTeX (Download)
@proceedings{APCPH2022-P-83,
title = {Predictive factors for severe COVID-19 infection in Terengganu state of Malaysia},
author = {Hafizuddin Awang and Azmani Wahab and Mohd Anuar Abd Rahman and Kasemani Embong},
url = {https://apcph.cphm.my/wp-content/uploads/2022/07/APCPH2022-P-83.pdf
https://apcph.cphm.my/wp-content/uploads/wpforms/1176-1e04940bb5d885bf8711ed19095a89ed/APCPH-POSTER-HAFIZUDDIN-P-83-a0a390e3957c36b0c680cb628e4ff473.pdf},
year = {2022},
date = {2022-08-02},
urldate = {2022-08-02},
issue = {7},
abstract = {Introduction: COVID-19 has a varied clinical presentation and may progress to severe form which could be fatal. Previous systematic reviews reported that 19.2% to 21.33% of COVID-19 patients progressed to severe form. Determination of risk factors for severe form of infection would be beneficial in averting COVID-19 mortality in Terengganu setting.
Methods: A case-control study between mild and severe COVID-19 groups was conducted in Terengganu state from 1st March 2020 until 31st January 2021 based on retrospective record review. Cases were severe COVID-19 patients (COVID-19 patients grouped in category IV or V upon diagnosis) while controls were mild COVID-19 patients (COVID-19 patients grouped in category I, II or III upon diagnosis). Individuals with laboratory RT-PCR confirmed positive test for COVID-19 were included as study samples. Descriptive statistics, simple and multiple logistic regression analyses were employed for statistical analysis. Results: There were 2142 COVID-19 cases in Terengganu during the studied period. The proportion of severe COVID-19 infection was 2.1% (95%CI: 0.01, 0.03). Among the severe COVID-19 cases, their mean ( ±SD) age was 52 ( ±16) and majority of them were male (59.1%) and had comorbidity (56.8%). The common symptoms among severe COVID-19 cases included fever (68.2%), cough (63.6%), coryza (22.7%), sore throat (13.6%) and anosmia (11.4%). Multiple logistic regression revealed older age, presence of comorbidity, having symptoms of fever, cough and anosmia as the significant associated factors for severe COVID-19 with adjusted odds ratio (AOR) of 1.07 (95%CI: 1.03, 1.11), p\<0.001; AOR 5.97 (95%CI: 2.09, 17.01)},
howpublished = {published online at https://apcph.cphm.my},
note = {Type: POSTER PRESENTATION; Organisation: Besut District Health Office, Kampung Raja, Besut, Terengganu; Terengganu State Health Department, Kuala Terengganu, Terengganu},
keywords = {},
pubstate = {published},
tppubtype = {proceedings}
}