Risk Factors of Severe Clinical Outcome Covid-19 Cases In Kulim, Kedah Between August And December 2021

Farah Fatin Fauzi, Elliza Mansor, Muhammad Suhail Abdul Wali, Cik Normadiah Said, Alias Abd. Aziz: Risk Factors of Severe Clinical Outcome Covid-19 Cases In Kulim, Kedah Between August And December 2021. published online at https://apcph.cphm.my, 2022, (Type: POSTER PRESENTATION; Organisation: Kulim District Health Office, Kedah; Universiti Putra Malaysia).

Abstract

Background: As of December 26, 2021, Malaysia had more than 2.7 million COVID-19 cases, with more than 166 thousand cases, or 6.1% reported in Kedah. Additionally, over 21% are from Kulim District, which makes this district among those with a high number of COVID-19 in Kedah. This study aimed to determine the risk factor of severe clinical outcomes of COVID-19 cases in Kulim, Kedah.
Methodology: This was a cross-sectional study utilising COVID-19 data gathered from routine daily district surveillance and collected by the Kulim COVID-19 Assessment Centre (CAC) between August 1 2021, and December 15 2021. From all 27649 subject data in the sampling frame, the final analysis included those that met the selection criteria using a simple random sampling method with a final sample size of 2269.
Results: From the final model of multiple logistic regression analysis, severe clinical outcome was found to be 56 times higher in those aged 60 years and more (aOR, 56.4; 95% CI, 12.61-252.38), followed by those in the age group of 46 to 59 years old (aOR, 7.31; 95% CI, 1.59-33.62). Unvaccinated COVID-19 patients were found to be 2.7 times more at risk of severe clinical outcomes (aOR, 2.7; 95% CI, 1.56-4.69) compared to those being fully vaccinated with two doses of COVID-19 vaccine cases. Having symptoms upon diagnosis of COVID-19 was also strongly a risk factor in developing severe clinical outcomes compared to those with asymptomatic cases (aOR, 10.03; 95% CI, 4.34-23.20). Conclusion: Age 60 years and more, unvaccinated and symptomatic upon the first diagnosis are among the risk factors contributing toward severe clinical outcomes of COVID-19. Thus, protecting the elderly, completed vaccination of COVID-19, and early screening should be emphasised in managing COVID-19 to prevent severe clinical outcomes.

BibTeX (Download)

@proceedings{APCPH2022-P-100,
title = {Risk Factors of Severe Clinical Outcome Covid-19 Cases In Kulim, Kedah Between August And December 2021},
author = {Farah Fatin Fauzi and Elliza Mansor and Muhammad Suhail Abdul Wali and Cik Normadiah Said and Alias Abd. Aziz},
url = {https://apcph.cphm.my/wp-content/uploads/2022/07/APCPH2022-P-100.pdf 
 
https://apcph.cphm.my/wp-content/uploads/wpforms/1176-1e04940bb5d885bf8711ed19095a89ed/Elliza-mansor_APCPH2022-P-100-20a6d1bd85bf4226d951ce0321ae1021.pdf},
year  = {2022},
date = {2022-08-02},
urldate = {2022-08-02},
issue = {7},
abstract = {Background: As of December 26, 2021, Malaysia had more than 2.7 million COVID-19 cases, with more than 166 thousand cases, or 6.1% reported in Kedah. Additionally, over 21% are from Kulim District, which makes this district among those with a high number of COVID-19 in Kedah. This study aimed to determine the risk factor of severe clinical outcomes of COVID-19 cases in Kulim, Kedah. 
Methodology: This was a cross-sectional study utilising COVID-19 data gathered from routine daily district surveillance and collected by the Kulim COVID-19 Assessment Centre (CAC) between August 1 2021, and December 15 2021. From all 27649 subject data in the sampling frame, the final analysis included those that met the selection criteria using a simple random sampling method with a final sample size of 2269. 
Results: From the final model of multiple logistic regression analysis, severe clinical outcome was found to be 56 times higher in those aged 60 years and more (aOR, 56.4; 95% CI, 12.61-252.38), followed by those in the age group of 46 to 59 years old (aOR, 7.31; 95% CI, 1.59-33.62). Unvaccinated COVID-19 patients were found to be 2.7 times more at risk of severe clinical outcomes (aOR, 2.7; 95% CI, 1.56-4.69) compared to those being fully vaccinated with two doses of COVID-19 vaccine cases. Having symptoms upon diagnosis of COVID-19 was also strongly a risk factor in developing severe clinical outcomes compared to those with asymptomatic cases (aOR, 10.03; 95% CI, 4.34-23.20). Conclusion: Age 60 years and more, unvaccinated and symptomatic upon the first diagnosis are among the risk factors contributing toward severe clinical outcomes of COVID-19. Thus, protecting the elderly, completed vaccination of COVID-19, and early screening should be emphasised in managing COVID-19 to prevent severe clinical outcomes.},
howpublished = {published online at https://apcph.cphm.my},
note = {Type: POSTER PRESENTATION; Organisation: Kulim District Health Office, Kedah; Universiti Putra Malaysia},
keywords = {characterisation, Covid-19, Kedah, Kulim, Risk Factor},
pubstate = {published},
tppubtype = {proceedings}
}