Abstract
BACKGROUND: Hepatitis C is a global public health concern both in developed and developing countries. However, evidences regarding risk factors for hepatitis C is not well explored before in Malaysia. The aim of the study was to assess risk factors associated with hepatitis C among adult patients in Kedah state, Malaysia. METHODS: A matched, hospital based, case-control study was conducted at a tertiary hospital in Kedah state. Cases were adults (aged ?18 years) diagnosed with hepatitis C between 2015-2018 while controls were age-, gender-, and ethnic-matched and tested negative for hepatitis C. Standard questionnaires on demographic and previous exposure to listed risk factors were filled up by all study participants. Association between hepatitis C, demographic and risk factors were assessed using logistic regression analysis. RESULTS: Total of 257 pairs case-control patients enrolled. Multivariate analysis indicate that blood or blood products transfusion (adjusted odd ratio [aOR] 6.81, 95% confidence intervals [CI]; 3.64, 13.40), injection drug use (aOR 6.29, 95% CI; 3.53, 11.68), body piercing (aOR 1.68, 95% CI; 1.03, 2.75), tattoo (aOR 3.77, 95% CI; 1.39, 12.11), been jailed (aOR 4.68, 95% CI; 1.67, 16.76), sexual promiscuity (aOR 1.93, 95% CI; 1.10, 3.44) and secondary education (aOR 1.90, 95% CI; 1.06, 3.53) were independently associated with hepatitis C. CONCLUSION: Parenteral routes were the main mode of transmission for hepatitis C identified beside sexual promiscuity. Healthcare givers may use this finding as a screening tool for early detection and timely interventions of hepatitis C in these high-risk groups in Malaysia.
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@proceedings{APCPH-2019-262,
title = {Risk Behaviors Associated with Hepatitis C Infection Among Adult Patients in Kedah State, Malaysia},
author = {Mohd Azri Mohd Suan and Salmiah Md Said and Lim Poh Ying and Ahmad Zaid Fattah Azman and Muhammad Radzi Abu Hassan},
year = {2019},
date = {2019-07-22},
urldate = {2019-07-22},
journal = {6th Asia-Pacific Conference on Public Health 2019 Proceedings},
issue = {6},
abstract = {BACKGROUND: Hepatitis C is a global public health concern both in developed and developing countries. However, evidences regarding risk factors for hepatitis C is not well explored before in Malaysia. The aim of the study was to assess risk factors associated with hepatitis C among adult patients in Kedah state, Malaysia. METHODS: A matched, hospital based, case-control study was conducted at a tertiary hospital in Kedah state. Cases were adults (aged ?18 years) diagnosed with hepatitis C between 2015-2018 while controls were age-, gender-, and ethnic-matched and tested negative for hepatitis C. Standard questionnaires on demographic and previous exposure to listed risk factors were filled up by all study participants. Association between hepatitis C, demographic and risk factors were assessed using logistic regression analysis. RESULTS: Total of 257 pairs case-control patients enrolled. Multivariate analysis indicate that blood or blood products transfusion (adjusted odd ratio [aOR] 6.81, 95% confidence intervals [CI]; 3.64, 13.40), injection drug use (aOR 6.29, 95% CI; 3.53, 11.68), body piercing (aOR 1.68, 95% CI; 1.03, 2.75), tattoo (aOR 3.77, 95% CI; 1.39, 12.11), been jailed (aOR 4.68, 95% CI; 1.67, 16.76), sexual promiscuity (aOR 1.93, 95% CI; 1.10, 3.44) and secondary education (aOR 1.90, 95% CI; 1.06, 3.53) were independently associated with hepatitis C. CONCLUSION: Parenteral routes were the main mode of transmission for hepatitis C identified beside sexual promiscuity. Healthcare givers may use this finding as a screening tool for early detection and timely interventions of hepatitis C in these high-risk groups in Malaysia.},
note = {Type: POSTER PRESENTATION; Organisation: Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Hospital Sultanah Bahiyah, Alor Setar, Kedah, Malaysia},
keywords = {case-control, hepatitis C, Malaysia, Risk Factor},
pubstate = {published},
tppubtype = {proceedings}
}