Abstract
INTRODUCTION: The aim of hypertension treatment is to reduce cardiovascular and renal morbidity and mortality. Medication adherence is a major cause of treatment failure. This study aimed to assess the association between medication adherence and uncontrolled hypertension. METHODS: A health clinic based unmatched case control study with 1:1 ratio was conducted among 334 hypertensive patients from a district of Penang. Cases were hypertensive patients with uncontrolled hypertension (BP?140/90mmHg), while controls were those with controlled hypertension (BP<140/90mmHg), selected by simple random sampling from appointment list. The independent variables were sociodemographic data, clinical factors and medication adherence. Data collection was done with validated interviewer assisted questionnaires and medical record reviews. RESULTS: The mean age of respondents was 59 years (SD=11), with majority were females (60%) and Malays (53%). Most had hypertension for less than five years (44%), with comorbidity (60%), were overweight or obese (80%), on two or more antihypertensive agents (55%), and once daily medication regime (92%). More than half of respondents (57%) were found to have poor medication adherence, which was among 83% of cases, and 31% of controls (p<0.001). Simple logistic regression showed poor medication adherence increased the odds of uncontrolled hypertension by 11 times compared to good medication adherence (OR: 11.29, 95%CI: 6.69, 19.05). Those using two or more antihypertensive agents increased the odds of uncontrolled hypertension by 1.6 times compared to those on single antihypertensive agent (OR: 1.63, 95%CI: 1.05, 2.51). CONCLUSION: Improving medication adherence is vital in tackling uncontrolled hypertension.
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@proceedings{APCPH-2019-286,
title = {The Association Between Medication Adherence and Uncontrolled Hypertension},
author = {Tan Hooi Shyuan and Ahmad Azuhairi Ariffin and Nor Afiah Mohd Zulkefli and Feisul Idzwan Mustapha},
year = {2019},
date = {2019-07-22},
urldate = {2019-07-22},
journal = {6th Asia-Pacific Conference on Public Health 2019 Proceedings},
issue = {6},
abstract = {INTRODUCTION: The aim of hypertension treatment is to reduce cardiovascular and renal morbidity and mortality. Medication adherence is a major cause of treatment failure. This study aimed to assess the association between medication adherence and uncontrolled hypertension. METHODS: A health clinic based unmatched case control study with 1:1 ratio was conducted among 334 hypertensive patients from a district of Penang. Cases were hypertensive patients with uncontrolled hypertension (BP?140/90mmHg), while controls were those with controlled hypertension (BP\<140/90mmHg), selected by simple random sampling from appointment list. The independent variables were sociodemographic data, clinical factors and medication adherence. Data collection was done with validated interviewer assisted questionnaires and medical record reviews. RESULTS: The mean age of respondents was 59 years (SD=11), with majority were females (60%) and Malays (53%). Most had hypertension for less than five years (44%), with comorbidity (60%), were overweight or obese (80%), on two or more antihypertensive agents (55%), and once daily medication regime (92%). More than half of respondents (57%) were found to have poor medication adherence, which was among 83% of cases, and 31% of controls (p\<0.001). Simple logistic regression showed poor medication adherence increased the odds of uncontrolled hypertension by 11 times compared to good medication adherence (OR: 11.29, 95%CI: 6.69, 19.05). Those using two or more antihypertensive agents increased the odds of uncontrolled hypertension by 1.6 times compared to those on single antihypertensive agent (OR: 1.63, 95%CI: 1.05, 2.51). CONCLUSION: Improving medication adherence is vital in tackling uncontrolled hypertension.},
note = {Type: POSTER PRESENTATION; Organisation: 1Department of Community Health, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Malaysia, 2Ministry of Health, MalaysiaMinistry of Health, Malaysia},
keywords = {case control study, hypertension, medication adherence},
pubstate = {published},
tppubtype = {proceedings}
}